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Acute
Coronary Syndromes |
Update
Management on ACS |
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Ischemic
Heart Disease
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Heart
diseases remain the second leading cause of death in Hong Kong
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Overall
fatality rate is around 30% with > 50% died within one hour,
mainly from ventricular fibrillation
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Acute Coronary
Syndromes
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- Plaque rupture causes release and
accumulation of thrombogenic substances |
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- Lumen occlusion by a combination of
fibrin, platelet aggregates and red blood cells |
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- Extent of lumen occlusion determines
the acute coronary syndrome produced |
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- A spectrum of clinical entities that composed of
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unstable angina |
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non-Q myocardial infarction |
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Q
wave myocardial infarction
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Pathology of
Acute Coronary Syndromes |
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Almost
all result from coronary atherosclerosis,
generally with superimposed coronary thrombosis
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